AMOXYCILLIN SODIUM INJ.
Amoxycillin Sodium Injection is a sterile, broad-spectrum penicillin for injection when oral therapy is inappropriate. Protech Telelinks is the manufacturer of Amoxycillin Sodium Injection for pharma marketers, PCD companies and institutional suppliers under their own brand through WHO GMP certified manufacturing partners.
What Is Amoxycillin Sodium Injection?
Dry powder form (semi-synthetic aminopenicillin) to be reconstituted with sterile water just prior to use; quickly attains therapeutic blood concentrations for severely ill or vomiting patients that are unable to swallow.
The basics: Amoxycillin is bactericidal. It inhibits peptidoglycan cross-linking in the bacterial cell wall by binding to transpeptidases, with subsequent cell lysis. It covers Streptococcus pneumoniae, S. pyogenes, non-penicillinase producing Staphylococcus, H. influenzae, E. coli and P. mirabilis, though it is not active against strains that produce β-lactamase, the strains which should then be treated with an amoxycillin + clavulanic acid combination.
Clinical Uses
- Respiratory: Community acquired pneumonia, bronchitis flare ups
- ENT: otitis media, sinusitis, pharyngitis/tonsillitis
- Urinary tract infections, including pyelonephritis
- Infections of the skin and soft tissues
- Systemic serious infections (meningitis, septicaemia, endocarditis) as recommended by the healthcare professional
- Endocarditis and surgical prophylaxis
Key Benefits
- Onset of action more rapid by IV route. Useful in the acutely ill and ICU setting.
- Slow IV injection, infusion over a short period of time or deep IM injection.
- Long safety history
- 250 mg, 500 mg and 1 g strengths for adult and paediatric dosing
- Cost-effective versus many broader-spectrum injectables
Reconstitution and Administration
Solution is unstable in concentrated form, made fresh when required and used immediately. Vials are single use. Dose, Frequency & Duration: decided by the treating physician on the basis of infection, age, weight & renal function. Dose is to be reduced when renal impairment is present. Use as per authorized package insert.
Safety Information
- Contraindicated: hypersensitivity to amoxycillin, penicillins or other beta-lactams
- Caution: renal failure, glandular fever (risk rash); prolonged treatment (blood, liver and kidney function monitor).
- Side effects: rash, urticaria, nausea, diarrhoea, pain at injection site, rarely severe allergic reactions or colitis caused by antibiotics.
- Interactions: probenecid, allopurinol, methotrexate, oral anticoagulants, contraceptives containing oestrogen
- Prescription-only: Follow use under the prescription of a registered health care professional may help reduce the development of antimicrobial resistance.
Why Choose Protech Telelinks?
In the following, there are reasons for trusting Protech Telelinks:
- WHO GMP certified manufacturing units
- Segregated penicillin-class and aseptic processing
- Raw material, in-process, sterility, endotoxin and assay testing, with batch CoA
- Your private label: your own logo, carton, leaflet & label
- Small MOQ, delivery on time
- Providing support to PCD marketers, distributors, hospitals and institutional supply stores
FAQs
What are the strengths of Amoxycillin Sodium Injection?
Amoxycillin Sodium Injection is available in the following strengths and pack sizes, with diluents and pack presentation designed to meet the needs of your brand. Contact us for availability of strengths and pack sizes. 250 mg; 500 mg; 1g.
Can I get my own brand name and packaging?
Yes. We provide custom private label manufacturing with your brand name, logo, carton, label and leaflet design, and artwork support which is regulatory compliant so that your product can go to market under your own identity.
Is this similar to Amoxycillin + Clavulanic Acid injection?
No. The product contains clavulanic acid, a beta-lactamase enzyme that extends the spectrum of amoxycillin. Plain Amoxycillin Sodium Injection is ineffective against beta-lactamase-producing bacteria. We can discuss the mixture independently.
Is Amoxycillin Sodium Injection suitable for children?
Yes, if under a doctor’s supervision. Paediatric doses are based on age and weight of the child and the treating doctor will decide the appropriate dose depending on the severity of infection. Not to be given on their own.
How should the reconstituted solution be handled?
Amoxycillin sodium is unstable in the concentrated form, and this should be reconstituted immediately prior to use and the same day. Any reconstituted solution should be used immediately and disposal of any solution remaining in the vial should take place, once the lid is removed it should not be reused. Administer in accordance with the licensed pack insert.
