Acyclovir for Injection USP

Acyclovir for Injection USP is a sterile, lyophilized antiviral indicated for the intravenous therapy of serious herpesvirus and varicella zoster virus infections. Acyclovir for Injection USP is a trusted medication used in hospitals and other medical facilities throughout the world to effectively treat patients in need of intravenous medication when oral therapy isn’t an option. Protech Telelinks, Inc. Provides high quality ready-to-use injectable Acyclovir for Injection to hospitals, physicians, distributors and other healthcare providers.

Product Overview

Acyclovir injection is a man-made version of a compound that is used to fight infections caused by the herpes simplex and varicella zoster viruses. It works by stopping the growth and multiplication of these viruses in your body. When this injection is introduced into your body, it is converted in the body to a form that treats the herpes zoster and herpes simplex viruses; thus, this can be used safely as an effective injection for in our mode of treatment. This Injection comes as a sterile-white lyo product for re-constitution before injection.

Key Features

• Injecting (intravenous injection): To get the medication into the blood quickly, sometimes when the patient has severe infection or is unable to eat.
• Innovative antiviral activity: Significant activity against herpes simplex virus (HSV-1, HSV-2) and the varicella-zoster virus.
• Lyophilized powder: Provides stability at storage, can be easily reconstituted at the time of use.
• Pharmacopeial quality: Made to USP specifications for strength, purity and sterility.
• Hospital fit: Approved for ward, ICU, paediatric and neonatal care when used as indicated.

Indications

The following conditions are controlled or prevented: Acyclovir for Injection USP is usually used for:

• Herpes simplex encephalitis in adults and children.
• Infections to neonates herpes simplify the baby for the period of up to three months.
• First and severe mucocutaneous and mucosal HSV infections in immunocompromised patients.
• First episodes of severe genital herpes in patients who are not immunocompromised.
• Infections of varicella-zoster (chickenpox and shingles) in persons with decreased immune resistance.

Dosage and Administration

The injection must be reconstituted as instructed with Sterile Water for Injection, then further diluted in an appropriate infusion fluid and given as a slow injection into a vein over around an hour, and is not to be given as a bolus injection. Dose and duration will vary according to severity of the infection, the age and body weight of the patient, and the function of the kidneys, and these must be at the discretion of a medical doctor. Large amounts of fluid should be given throughout therapy in order to keep the kidneys well hydrated.

Safety Information

Acyclovir is usually well tolerated when appropriately used. Side effects: may include local irritation at infusion site, nausea, rash, transient alterations in kidney function or liver enzyme levels, agitation or tremor (less common). Contraindications: hypersensitivity to acyclovir or valacyclovir.

Precautions: Renal impairment may require dose adjustment, vigilance in elderly and in pregnancy and lactation.

Adverse effects: Confusion or tremor ( less common) may also occur in patients with renal impairment.

Storage and Handling

Keep the unopened vials at room temperature in an environment that is light protected and dry. The solution in the vials should not be refrigerated after reconstitution because it may cause precipitation and should be used within the specified time stated in the written prescribing information. Discard unused material.

Why Choose Protech Telelinks

Protech Telelinks believes in support and not just products. Genuine Quality assured pharmaceuticals backed by a strong, efficient and responsive team of experts who are here to help. Stocks for Hospitals, Chemists and Healthcare Distributors, we are your first port of call for all supply and order requirements.

FAQs

How is Acyclovir for Injection administered?

This product is reconstituted with 1.5 ml (7.5 molars) of Sterile Water for Injections (see section 2.1) added to the vial, and then diluted in an infusion fluid suitable for the patient and reconstituted to the required volume and administered slowly. It should be administered as a slow infusion over approximately 1 hour. It must not be administered as an intravenous injection.

Who should not take or use this medication properly?

Patients who have previous hypersensitivity to any form of acyclovir or valacyclovir. Has kidney disease or impairment, elderly and pregnant women/ nursing women. Use with caution and adjust the dose if possible under the advice of the doctor.

What are the common side effects?

Potential side effects are infusion-site irritation, nausea, rash, and modest shifts in kidney function or liver enzymes. Infrequently, kidney or liver disturbances may be detected with temporarily altered kidney function or liver enzymes or, in the occasional case, confusion or tremor, in particular in patients with markedly compromised renal function.

How should the vials be stored?

Store unopened vials at controlled room temperature in a place with no light or moisture. Do not use reconstituted solution if it has been kept in a refrigerator because it may cause the solution to crystallize; discard any remnants.

Do you need a prescription to purchase?

Yes, Acyclovir for Injection USP is available for use with a Prescription from a Registered Healthcare Practitioner and must be administered by a qualified Healthcare Professional.